An aortic dissection is an often fatal disorder in which the inner layer lining of the aortic wall tears and separates from the middle layer of the aortic wall. Aortic dissection stanford classification type a type b ascend. Aortic dissection is caused by an intimal and medial tear in the aorta with propagation of a false lumen within the aortic media. Stanford classification of aortic dissection radiology. Essential treatment includes rapid initiation of pharmacologic agents to control hypertension. This can lead to aortic rupture or decreased blood flow ischemia to organs. Surgical repair in the acute dstal aortic dissection phase is associated with high morbidity and mortality. Lindsay is initiating a largescale collection of genetic samples from people who have experienced aortic dissection. As has been stated before, type a dissections require immediate surgical repair. A 61yearold man with history of chronic hypertension presented with a oneday history of chest pain, vertigo, left facial drooping, and left hemiparesis.
Symptoms and clinical findings often depend on the extent and involvement of dissection. Feb 22, 2010 aortic dissection zahir rahman md 101402 slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. An extensive stanford type a aortic dissection involving. The objective of this study is to use computational fluid dynamics reconstructions of type b aortic dissections to. Aortic dissections in the elderly pubmed central pmc. The timing and need for intervention surgicalendovascular differs for ascending type a and descending type b. Surgery for aortic dissection surgeons either insert a tube called a stent to prevent blood from flowing into the false lumen that forms between the layers of the aorta during a dissection, or they replace the damaged parts of the aorta with a synthetic material. New paradigms in the treatment of acute complicated and uncomplicated type b aortic dissection. Aortic dissection is the retinal detachment of the torso on pocus. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Mainoutcomemeasures presenting history, physical findings, management, and. Irad is a multicenter registry of all cases of acute aortic dissection at participating sites.
Patients with type b aortic dissection often present as a spectrum of acute aortic syndromes, including intramural hematoma, penetrating aortic ulcers, aortic dissection and aneurysms. Aortic dissection heart and blood vessel disorders merck. The most important inherited connective tissue diseases involving the aortic wall are marfan syndrome mfs and ehlersdanlos syndrome eds, along with the familial types of thoracic aortic aneurysm and aortic dissection. Surgeons either insert a tube called a stent to prevent blood from flowing into the false lumen that forms between the layers of the aorta during a dissection, or they replace the damaged parts of the aorta with a synthetic material. For untreated acute dissection of the ascending aorta, the mortality rate is 12% per hour early after symptom onset. Journal jam 9 ddimer to rule out aortic dissection view larger image the em cases team is very excited to bring you not only a new format for the journal jam podcast but a new member of the team, dr. Pdf acute type a aortic dissection involving the iliac. Tears in the intimal layer result in the propagation of dissection proximally or distally secondary to blood entering the intimamedia space. The rate of aortic dissection was higher during the pregnancy and postpartum period 5.
A new mnemonicbased approach to the categorization of aortic dissection m. Abrupt and severe retrosternal or inter scapular chest pain is sometimes felt as a tear, with subsequent migration down the back occurs in 90% of patients. Aortic dissection is a medical emergency and can quickly lead to death should the bloodfilled section rupture through the outside aortic wall. The estimated incidence is 530 cases per million people per year. Pdf acute aortic dissection is the most frequent and deadly presentation of acute aortic syndromes. Aortic dissection information guide a o r t i c d i s s e c t i o n m a r d i g i a n w e l l n e s s r e s o u r c e c e n t e r page 1. Findings are published in the annals of thoracic surgery.
As the tear extends along the wall of the aorta, blood can flow in between the layers of the blood vessel wall dissection. Mortality is still high despite advances in diagnostic and therapeutic modalities. While the sensitivity of pocus by ed physicians to detect an intimal flap is only 67%, the specificity has been shown to be 99100%. Acute aortic syndromes are a constellation of lifethreatening medical conditions, including classic acute aortic dissection aad, intramural haematoma imh, penetrating atherosclerotic aortic ulcer pau even thoracic aortic rupture, which share common pathophysiological pathways breakdown of the intima and media, clinical. The longterm, multicenter project may generate predictive tests and targeted preventative and therapeutic strategies. If this is seen, and there is a high clinical suspicion of a dissection, a ct scan of the chest with. As a trainee, i read the chapters discussing all the classifications and discussions of the biomechanics and felt quite intimidated by the all the moving parts involved in an aortic dissection, and i missed the main point about tbad. Combined thoracic aortic dissection and abdominal aortic. Aortic dissection red flags for the emergency triage nurse e m e r g e n c y m e d ic n e c a m p a i g n publishedbythe nationalmarfanfoundation. Prompt diagnosis and management of aortic dissection are key to reduce patient morbidity and mortality. However, it was not until the midtwentieth century that the first large case series was published and the first surgical resection was performed. It receives oxygenrich blood from the heart and distributes it to the body through smaller.
Look for marphans, listen for an aortic regurgitation murmur. It is part of the acute aortic syndrome an umbrella term for aortic dissection, intramural haematoma, and symptomatic aortic ulcer table. This study, using the international registry of aortic dissection irad, helps elucidate patient and disease characteristics associated with recurrent aortic dissection. For a deep dive into the worlds literature on ddimer for aortic dissection visit em cases journal jam 9. Dec 18, 2019 a false lumen yellow arrow is seen in the above aortic dissection in the united states, aortic dissection occurs most frequently in hypertensive patients. Aortic dissection an overview sciencedirect topics. Uncomplicated acute type b aortic dissections are usually treated medically, but they can become acutely complicated by rapid expansion, rupture and malperfusion syndromes and in the longer term by chronic dilatation and aortic aneurysm formation. In 22 of 48 46% patients, raad occurred within the first 30 days. The debakey classification system is an anatomical description of the aortic dissection figure 6. The surgery involved in repairing an aortic dissection is very difficult and invasive.
The initial management for an aortic dissection often occurs in the emergency room. A patient has an intravenous iv line placed, so that medications can be delivered directly into the blood stream. Aortic dissection zahir rahman md 101402 slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. I used meshmixer to add the supports and combine the two segments. During the first two weeks acute phase, lifethreatening complications due to branch involvement or aortic rupture are more likely to occur compared with the timeframe past two weeks chronic phase. Apr 14, 2017 one file has supports built into the design, if you are printing on a fdm printer. The extent of a dissection is classified using one of two systems. An aortic dissection is a serious condition in which the inner layer of the aorta, the large blood vessel branching off the heart, tears. Perhaps nowhere is this shift in approach more apparent than in the treatment of acute aortic.
An aortic dissection, or tear in the aorta, typically occurs when the inner layer of the arterys wall weakens. The double barrel appearance in cross section of the aorta means that the physiologic pressure of the of a single channel of flowing blood in the normal. Aortic dissection is a catastrophic cardiovascular condition first described in detail by frank nicholls in his necropsy report of king george ii. Type b aortic dissections tbad are frequently seen here at the clinic as we serve as a regional referral center. Two populationbased studies indicated incidences of 2. The incidence of type a dissection was greater among men, with the average ratio of 3. A false lumen yellow arrow is seen in the above aortic dissection in the united states, aortic dissection occurs most frequently in hypertensive patients. The em cases team is very excited to bring you not only a new format for the journal jam podcast but a new member of the team, dr. Blood can pass through the tear into the middle layer of the wall, causing the layers to separate from one another, or dissect. Red flags for the emergency triage nurse published by the nationalmarfanfoundation 22manhassetavenue portwashington,ny11050. Aortic dissection surgery saves lives and funds research.
Aortic dissection and its variants stanford university. The goals of early management of aortic dissection are to control pain and limit the extension of the dissection using antiimpulse therapy, which typically involves administration of beta blockers and control of blood pressure. The intimal tear may be a primary event or secondary to hemorrhage within the media. This system takes into account the location of the original intimal tear and the extent of the dissection. The dissection may occur anywhere along the aorta and extend proximally or distally into other arteries. The international registry of acute aortic dissection irad. New type a dissection after acute type b aortic dissection. Aortic dissection, though uncommon, when it occurs, it is most frequently in men aged 60 to 70. Although his death marked the end of an era, the circumstances surrounding the surgery for his acute dissection revealed all of the challenges that we as cardiovascular surgeons face when treating the elderly.
Ddimer rule out aortic dissection em cases journal. Aortic dissection is the surging of blood through a tear in the aortic intima with separation of the intima and media and creation of a false lumen channel. The incidence of acute aortic dissection has been estimated to be approximately 3 per 100,000 persons, but more recently the rate has increased to 6 per 100,000. If aortic dissection is suspected, the patient must immediately be taken to a cardiovascular surgery center with an emergency physician in attendance. We sought to determine associations for development of proximal progression or new type a aortic dissection ntad after acute type b dissection atbd and its effect on survival of the patient. Aortic dissection is a relatively rare but highly lethal disease. A small tear forms in this layer, and, if left untreated, it can enlarge. Retrograde ascending aortic dissection during or after. A new study shows improved patient outcomes with extensive repair of aortic dissection. Aortic dissection cardiovascular disorders merck manuals.
In addition it strongly emphasizes basic principles in medicine. Retrograde ascending aortic dissection occurred during the tevar procedure n 7, 15%, before the procedure during the index hospitalization n 10, 21%, and after discharge during followup n 31, 65% table 3 and figure 1. Aortic dissection is the most common catastrophic condition affecting the aorta. Aortic dissection is a more common problem than is ruptured abdominal aortic aneurysm. Usually the causative factor is an underlying disease of the media. Aortic dissection is a tear in the wall of the aorta which causes the inner and middle layers of the aorta to separate. Both false and true lumina are patent with no evidence of occlusion of any of the aortic branches. Aortic dissection is classified, somewhat arbitrarily, as acute or chronic based upon the duration of symptoms at the time of presentation. Continuing on with the theme of acute aortic dissections, lets discuss in more detail the ramifications and consequences of blood simultaneously flowing in two separate, parallel channels within the aorta. Combined use of aortic dissection detection risk score and ddimer in the diagnostic workup of suspected acute aortic dissection. The flap is seen involving the ascending aorta, without involvement of the coronaries, the arch and descending aorta and extends distally to the aortic bifurcation. Type a aortic dissection after nonaortic cardiac surgery. Arterial hypertension is an important predisposing factor for aortic dissection. Blood surges through the tear, causing the inner and middle layers of the aorta to separate dissect.
Dissection can be classified by the sites involved. Aortic dissection uf health, university of florida health. The authors describe dissections that originate from the arch or extend proximally into the arch without the involvement of the. Remember the big pain pearls when taking a history. In 2014, a special report was published in radiology 4 that recognized an uncommon form of aortic dissection. Mfs is the most frequent congenital connective tissue disorder, occurring in 1 in 7000 births with autosomal dominant inheritance. What is the classic clinical presentation of a dissecting aorta. Jan 08, 2019 aortic dissection see the image below is defined as separation of the layers within the aortic wall. Blood pressure is reduced with medications, usually to 100 to 120 mmhg systolic. Management of acute aortic dissection christoph a nienaber, rachel e clough a new appraisal of the management of acute aortic dissection is timely because of recent developments in diagnostic strategies including biomarkers and imaging, endograft design, and surgical treatment, which have led to a better. Ddimer rule out aortic dissection em cases journal jam. Drawing of the aorta in a 63yearold man who had an acute myocardial infarct at age 60 years that healed.
Dake md, in comprehensive vascular and endovascular surgery second edition, 2009. Aortic dissection heart and blood vessel disorders. Eagle, md,x valentin fuster, md, phd abstract aortic dissection is the most devastating complication of thoracic aortic disease. The objective of this study is to use computational fluid dynamics reconstructions of type b aortic dissections to compare geometric and. Chest xray will sometimes show a widened mediastinum. We present a rare case of continuous, extensive aortic dissection ad involving the bilateral common carotid arteries, the ascending, thoracic, and abdominal aorta, and bifurcation of the right common iliac artery. When an aortic dissection is detected early and treated promptly, chance of survival greatly improves. Geometric and flow features of type b aortic dissection.
Its clinical presentation is variable and can mimic any number of medical and surgical conditions. Take home points for aortic dissection diagnosis and management. Modeling of predissection aortic size in acute type a. We believe its important to report this case because it underscores the relationship between cocaine abuse and aortic dissection. New paradigms in the treatment of acute complicated and. Aortic dissection is a dynamic process that can progress both proximal and distal to the initial entry tear. Participants a total of 464 patients mean age, 63 years. Aortic dissection involves a tear in the medial layer of the aortic wall, causing blood to extravasate into the media and thus compromising blood flow to the brain, heart, and other organs. This occurs because the enlarged aorta casts a larger shadow on the xray detector. Other studies were omitted due to methodological limitations. In the operating room, a cardiothoracic surgeon first performs a median sternotomy, a procedure in which a patients chest is opened. If you continue browsing the site, you agree to the use of cookies on this website. Sep 19, 2008 acute aortic dissection is often accompanied by sudden stabbing back pain 53%, which sometimes follows the course of the aorta in craniocaudal direction 17%. The most prevalent symptom is excruciating chest pain.
Acute type b aortic dissection comprises approximately onethird of all aortic dissection cases. If the bloodfilled channel ruptures through the outside aortic wall, aortic dissection is often fatal. Not defined in stanford classification aortic arch. Although this catastrophic cardiovascular condition was first described in the medical literature over two centuries ago, data on the optimal diagnostic and treatment modalities for type b dissection was slow to evolve throughout the latter half of the twentieth century, even as newer diagnostic. Morales e, on behalf of the define investigators objectivebackground.
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